Human Steroidogenic Factor 1 (NR5A1) activation kit by CRISPRa

SKU GA101667

NR5A1 CRISPRa kit - CRISPR gene activation of human nuclear receptor subfamily 5 group A member 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NR5A1
• Locus ID: 2516
• Components:

  GA101667G1, Steroidogenic Factor 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101667G2, Steroidogenic Factor 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101667G3, Steroidogenic Factor 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_004959
• UniProt ID: Q13285
• Synonyms: AD4BP; ELP; FTZ1; FTZF1; hSF-1; POF7; SF-1; SF1; SPGF8; SRXY3
• Summary: The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. [provided by RefSeq, Jul 2008]