Human FOLR2 activation kit by CRISPRa

SKU
GA101646
FOLR2 CRISPRa kit - CRISPR gene activation of human folate receptor beta
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol FOLR2
Locus ID 2350
Components

GA101646G1, FOLR2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101646G2, FOLR2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101646G3, FOLR2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000803, NM_001113534, NM_001113535, NM_001113536
UniProt ID P14207
Synonyms BETA-HFR; FBP; FBP/PL-1; FR-BETA; FR-P3
Summary The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN412993 FOLR2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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