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Human PSMA (FOLH1) activation kit by CRISPRa

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SKU
GA101644
FOLH1 CRISPRa kit - CRISPR gene activation of human folate hydrolase 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA504752 FOLH1 mouse monoclonal antibody, clone OTI3H5 (formerly 3H5) 100 ul
$447.00
RC218310 FOLH1 (Myc-DDK-tagged)-Human folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 1
10 ug
$687.00

Other products for "FOLH1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol FOLH1
Locus ID 2346
Components

GA101644G1, PSMA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101644G2, PSMA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101644G3, PSMA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001014986, NM_001193471, NM_001193472, NM_001193473, NM_004476, NM_001351236
UniProt ID Q04609
Synonyms FGCP; FOLH; GCP2; GCPII; mGCP; NAALAD1; NAALAdase; PSM; PSMA
Summary This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. provided by RefSeq, Jul 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN206548 FOLH1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206548BN FOLH1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206548LP FOLH1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206548RB FOLH1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN406548 FOLH1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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