Human FOXD4 activation kit by CRISPRa

SKU GA101608

FOXD4 CRISPRa kit - CRISPR gene activation of human forkhead box D4

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: FOXD4
• Locus ID: 2298
• Components:

  GA101608G1, FOXD4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101608G2, FOXD4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101608G3, FOXD4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_207305
• UniProt ID: Q12950
• Synonyms: FKHL9; FOXD4A; FREAC-5; FREAC5
• Summary: This gene encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors. FOX transcription factors play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expression during ontogenesis. Mutations in this gene are associated with a complex phenotype consisting of dilated cardiomyopathy, obsessive-compulsive disorders, and suicidality. [provided by RefSeq, Mar 2012]