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Human FHIT activation kit by CRISPRa

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SKU
GA101592
FHIT CRISPRa kit - CRISPR gene activation of human fragile histidine triad diadenosine triphosphatase
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA811440 FHIT mouse monoclonal antibody,clone OTI1D7 100 ul
$447.00
RC207120 FHIT (Myc-DDK-tagged)-Human fragile histidine triad gene (FHIT), transcript variant 1
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Other products for "FHIT"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol FHIT
Locus ID 2272
Components

GA101592G1, FHIT gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101592G2, FHIT gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101592G3, FHIT gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001166243, NM_001320899, NM_001320900, NM_001320901, NM_002012, NR_135491, NM_001354589, NM_001354590, NR_148921, NR_148922
UniProt ID P49789
Synonyms AP3Aase; FRA3B
Summary The protein encoded by this gene is a P1-P3-bis(5'-adenosyl) triphosphate hydrolase involved in purine metabolism. This gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. The encoded protein is also a tumor suppressor, as loss of its activity results in replication stress and DNA damage. provided by RefSeq, Aug 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN407120 FHIT - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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