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Human MS4A2 activation kit by CRISPRa

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SKU
GA101544
MS4A2 CRISPRa kit - CRISPR gene activation of human membrane spanning 4-domains A2
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC210371 MS4A2 (Myc-DDK-tagged)-Human membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for, beta polypeptide) (MS4A2)
10 ug
$300.00

Other products for "MS4A2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MS4A2
Locus ID 2206
Components

GA101544G1, MS4A2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101544G2, MS4A2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101544G3, MS4A2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000139, NM_001142303, NM_001256916
UniProt ID Q01362
Synonyms APY; ATOPY; FCER1B; FCERI; IGEL; IGER; IGHER; MS4A1
Summary The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of membrane-spanning 4A gene family members. Alternative splicing results in multiple transcript variants encoding distinct proteins. Additional transcript variants have been described but require experimental validation. provided by RefSeq, Mar 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN410371 MS4A2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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