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Human Factor IX (F9) activation kit by CRISPRa

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SKU
GA101503
F9 CRISPRa kit - CRISPR gene activation of human coagulation factor IX
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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Other products for "F9"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol F9
Locus ID 2158
Components

GA101503G1, Factor IX gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101503G2, Factor IX gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101503G3, Factor IX gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000133, NM_001313913
UniProt ID P00740
Synonyms FIX; HEMB; P19; PTC; THPH8
Summary This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. provided by RefSeq, Sep 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN419065 F9 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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