Human CSB (ERCC6) activation kit by CRISPRa

SKU
GA101451
ERCC6 CRISPRa kit - CRISPR gene activation of human ERCC excision repair 6, chromatin remodeling factor
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ERCC6
Locus ID 2074
Components

GA101451G1, CSB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101451G2, CSB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101451G3, CSB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_000124, NM_001277058, NM_001277059, NM_001346440
UniProt ID Q03468
Synonyms ARMD5; CKN2; COFS; COFS1; CSB; RAD26; UVSS1
Summary This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Alternative splicing occurs between a splice site from exon 5 of this gene to the 3' splice site upstream of the open reading frame (ORF) of the adjacent gene, piggyback-derived-3 (GeneID:267004), which activates the alternative polyadenylation site downstream of the piggyback-derived-3 ORF. The resulting transcripts encode a fusion protein that shares sequence with the product of each individual gene. provided by RefSeq, Mar 2016
Reviews
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
KN219020 ERCC6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN219020BN ERCC6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN219020LP ERCC6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN219020RB ERCC6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN419020 ERCC6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products