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Human XPG (ERCC5) activation kit by CRISPRa

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SKU
GA101450
ERCC5 CRISPRa kit - CRISPR gene activation of human ERCC excision repair 5, endonuclease
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC201994 ERCC5 (Myc-DDK-tagged)-Human excision repair cross-complementing rodent repair deficiency, complementation group 5 (ERCC5)
10 ug
$1,032.00

Other products for "ERCC5"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ERCC5
Locus ID 2073
Components

GA101450G1, XPG gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101450G2, XPG gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101450G3, XPG gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000123
UniProt ID P28715
Synonyms COFS3; ERCC5-201; ERCM2; UVDR; XPG; XPGC
Summary This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, cognitive disability, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene. provided by RefSeq, Feb 2011
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Documents
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Other Versions
SKU Description Size Price
KN401994 ERCC5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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