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Human XPD (ERCC2) activation kit by CRISPRa

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SKU
GA101445
ERCC2 CRISPRa kit - CRISPR gene activation of human ERCC excision repair 2, TFIIH core complex helicase subunit
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA804192 ERCC2 mouse monoclonal antibody, clone OTI4B11 (formerly 4B11) 100 ul
$447.00
RC215058 ERCC2 (Myc-DDK-tagged)-Human excision repair cross-complementing rodent repair deficiency, complementation group 2 (ERCC2), transcript variant 1
10 ug
$696.00

Other products for "ERCC2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ERCC2
Locus ID 2068
Components

GA101445G1, XPD gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101445G2, XPD gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101445G3, XPD gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000400, NM_001130867
UniProt ID P18074
Synonyms COFS2; EM9; TFIIH; TTD; TTD1; XPD
Summary The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Aug 2008
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Documents
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Other Versions
SKU Description Size Price
KN415058 ERCC2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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