Human EPB4IL2 (EPB41L2) activation kit by CRISPRa

SKU GA101416

EPB41L2 CRISPRa kit - CRISPR gene activation of human erythrocyte membrane protein band 4.1 like 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: EPB41L2
• Locus ID: 2037
• Components:

  GA101416G1, EPB4IL2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101416G2, EPB4IL2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101416G3, EPB4IL2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001135554, NM_001135555, NM_001199388, NM_001199389, NM_001252660, NM_001431, NM_001350299, NM_001350301, NM_001350302, NM_001350303, NM_001350304, NM_001350305, NM_001350306, NM_001350307, NM_001350308, NM_001350309, NM_001350310, NM_001350311, NM_001350312, NM_001350313, NM_001350314, NM_001350315, NM_001350320, NR_146620
• UniProt ID: O43491
• Synonyms: 4.1-G; 4.1G
• Summary: Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase (PubMed:23870127).[UniProtKB/Swiss-Prot Function]