Human ELK4 activation kit by CRISPRa

SKU GA101390

ELK4 CRISPRa kit - CRISPR gene activation of human ETS transcription factor ELK4

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: ELK4
• Locus ID: 2005
• Components:

  GA101390G1, ELK4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101390G2, ELK4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101390G3, ELK4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001973, NM_021795
• UniProt ID: P28324
• Synonyms: SAP1
• Summary: This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is phosphorylated by the kinases, MAPK1 and MAPK8. Several transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]