Human MEGF8 activation kit by CRISPRa

SKU GA101353

MEGF8 CRISPRa kit - CRISPR gene activation of human multiple EGF like domains 8

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MEGF8
• Locus ID: 1954
• Components:

  GA101353G1, MEGF8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101353G2, MEGF8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101353G3, MEGF8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001271938, NM_001410
• UniProt ID: Q7Z7M0
• Synonyms: C19orf49; CRPT2; EGFL4; SBP1
• Summary: The protein encoded by this gene is a single-pass type I membrane protein of unknown function that contains several EGF-like domains, Kelch repeats, and PSI domains. Defects in this gene are a cause of Carpenter syndrome 2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]