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Human DYRK1A activation kit by CRISPRa

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SKU
GA101306
DYRK1A CRISPRa kit - CRISPR gene activation of human dual specificity tyrosine phosphorylation regulated kinase 1A
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC213183 DYRK1A (Myc-DDK-tagged)-Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A), transcript variant 2
10 ug
$1,035.00

Other products for "DYRK1A"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DYRK1A
Locus ID 1859
Components

GA101306G1, DYRK1A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101306G2, DYRK1A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101306G3, DYRK1A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001396, NM_101395, NM_130436, NM_130437, NM_130438, NM_001347721, NM_001347722, NM_001347723
UniProt ID Q13627
Synonyms DYRK; DYRK1; HP86; MNB; MNBH; MRD7
Summary This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN412584 DYRK1A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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