OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Human DNMT3B activation kit by CRISPRa

Be the first to review this product
SKU
GA101245
DNMT3B CRISPRa kit - CRISPR gene activation of human DNA methyltransferase 3 beta
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC223206 DNMT3B (Myc-DDK-tagged)-Human DNA (cytosine-5-)-methyltransferase 3 beta (DNMT3B), transcript variant 1
10 ug
$1,171.00

Other products for "DNMT3B"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DNMT3B
Locus ID 1789
Components

GA101245G1, DNMT3B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101245G2, DNMT3B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101245G3, DNMT3B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001207055, NM_001207056, NM_006892, NM_175848, NM_175849, NM_175850
UniProt ID Q9UBC3
Synonyms ICF; ICF1; M.HsaIIIB
Summary CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. provided by RefSeq, May 2011
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
KN221966 DNMT3B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN221966BN DNMT3B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN221966LP DNMT3B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN221966RB DNMT3B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN421966 DNMT3B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products