Human Dynamin 2 (DNM2) activation kit by CRISPRa

SKU
GA101241
DNM2 CRISPRa kit - CRISPR gene activation of human dynamin 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DNM2
Locus ID 1785
Components

GA101241G1, Dynamin 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101241G2, Dynamin 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101241G3, Dynamin 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001005360, NM_001005361, NM_001005362, NM_001190716, NM_004945
UniProt ID P50570
Synonyms CMT2M; CMTDI1; CMTDIB; DI-CMTB; DYN2; DYNII; LCCS5
Summary Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. provided by RefSeq, Jun 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN208525 DNM2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208525BN DNM2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208525LP DNM2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208525RB DNM2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN408525 DNM2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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