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Human DNase I (DNASE1) activation kit by CRISPRa

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SKU
GA101232
DNASE1 CRISPRa kit - CRISPR gene activation of human deoxyribonuclease 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA308546 Rabbit Polyclonal antibody to DNase I (deoxyribonuclease I)
100 ul
$665.00
RC205927 DNASE1 (Myc-DDK-tagged)-Human deoxyribonuclease I (DNASE1)
10 ug
$450.00

Other products for "DNASE1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DNASE1
Locus ID 1773
Components

GA101232G1, DNase I gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101232G2, DNase I gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101232G3, DNase I gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_005223, NM_001351825
UniProt ID P24855
Synonyms DNL1; DRNI
Summary This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
KN405927 DNASE1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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