Human SEPTIN1 activation kit by CRISPRa

SKU GA101201

SEPTIN1 CRISPRa kit - CRISPR gene activation of human septin 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: SEPTIN1
• Locus ID: 1731
• Components:

  GA101201G1, SEPTIN1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101201G2, SEPTIN1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101201G3, SEPTIN1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_052838, NM_001365977
• UniProt ID: Q8WYJ6
• Synonyms: DIFF6; LARP; PNUTL3; SEP1
• Summary: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]