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Human Factor D (CFD) activation kit by CRISPRa

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SKU
GA101185
CFD CRISPRa kit - CRISPR gene activation of human complement factor D
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA342870 Rabbit Polyclonal Anti-CFD Antibody
100 ul
$585.00
RC209272 CFD (Myc-DDK-tagged)-Human complement factor D (adipsin) (CFD)
10 ug
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Other products for "CFD"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CFD
Locus ID 1675
Components

GA101185G1, Factor D gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101185G2, Factor D gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101185G3, Factor D gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001317335, NM_001928
UniProt ID P00746
Synonyms ADIPSIN; ADN; DF; PFD
Summary This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. provided by RefSeq, Nov 2015
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Documents
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Other Versions
SKU Description Size Price
KN409272 CFD - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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