Human alpha 5 Defensin (DEFA5) activation kit by CRISPRa

SKU
GA101180
DEFA5 CRISPRa kit - CRISPR gene activation of human defensin alpha 5
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DEFA5
Locus ID 1670
Components

GA101180G1, alpha 5 Defensin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101180G2, alpha 5 Defensin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101180G3, alpha 5 Defensin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_021010
UniProt ID Q01523
Synonyms DEF5; HD-5
Summary Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum. provided by RefSeq, Oct 2014
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Other Versions
SKU Description Size Price
KN410219 DEFA5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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