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Human DAXX activation kit by CRISPRa

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SKU
GA101139
DAXX CRISPRa kit - CRISPR gene activation of human death domain associated protein
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ug
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RC226603 DAXX (Myc-DDK-tagged)-Human death-domain associated protein (DAXX), transcript variant 1
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Other products for "DAXX"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DAXX
Locus ID 1616
Components

GA101139G1, DAXX gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101139G2, DAXX gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101139G3, DAXX gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001141969, NM_001141970, NM_001254717, NM_001350, NR_024517
UniProt ID Q9UER7
Synonyms BING2; DAP6; EAP1
Summary This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. provided by RefSeq, Nov 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN419497 DAXX - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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