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Human Cytochrome p450 2C19 (CYP2C19) activation kit by CRISPRa

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SKU
GA101098
CYP2C19 CRISPRa kit - CRISPR gene activation of human cytochrome P450 family 2 subfamily C member 19
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC211377 CYP2C19 (Myc-DDK-tagged)-Human cytochrome P450, family 2, subfamily C, polypeptide 19 (CYP2C19)
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Other products for "CYP2C19"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CYP2C19
Locus ID 1557
Components

GA101098G1, Cytochrome p450 2C19 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101098G2, Cytochrome p450 2C19 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101098G3, Cytochrome p450 2C19 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000769
UniProt ID P33261
Synonyms CPCJ; CYP2C; CYPIIC17; CYPIIC19; P450C2C; P450IIC19
Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN411377 CYP2C19 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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