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Human CREBL2 activation kit by CRISPRa

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SKU
GA100975
CREBL2 CRISPRa kit - CRISPR gene activation of human cAMP responsive element binding protein like 2
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC210722 CREBL2 (Myc-DDK-tagged)-Human cAMP responsive element binding protein-like 2 (CREBL2)
10 ug
$150.00

Other products for "CREBL2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CREBL2
Locus ID 1389
Components

GA100975G1, CREBL2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100975G2, CREBL2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100975G3, CREBL2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001310
UniProt ID O60519
Synonyms MGC117311; MGC138362
Summary cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoietic malignancies, as well as breast, non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN410722 CREBL2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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