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Human KAT3A / CBP (CREBBP) activation kit by CRISPRa

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SKU
GA100973
CREBBP CRISPRa kit - CRISPR gene activation of human CREB binding protein
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA322757 Anti-CREBBP Rabbit Polyclonal Antibody
100 ul
$305.00
RC219036 CREBBP (Myc-DDK-tagged)-Human CREB binding protein (CREBBP), transcript variant 1
10 ug
$3,022.00

Other products for "CREBBP"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CREBBP
Locus ID 1387
Components

GA100973G1, KAT3A / CBP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100973G2, KAT3A / CBP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100973G3, KAT3A / CBP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001079846, NM_004380
UniProt ID Q92793
Synonyms CBP; KAT3A; RSTS
Summary This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Feb 2009
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Documents
Resources
Other Versions
SKU Description Size Price
KN216439 CREBBP - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216439BN CREBBP - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216439LP CREBBP - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216439RB CREBBP - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN416439 CREBBP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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