Human COL13A1 activation kit by CRISPRa

SKU GA100918

COL13A1 CRISPRa kit - CRISPR gene activation of human collagen type XIII alpha 1 chain

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: COL13A1
• Locus ID: 1305
• Components:

  GA100918G1, COL13A1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100918G2, COL13A1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100918G3, COL13A1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001130103, NM_005203, NM_080798, NM_080799, NM_080800, NM_080801, NM_080802, NM_080803, NM_080804, NM_080805, NM_080806, NM_080807, NM_080808, NM_080809, NM_080810, NM_080811, NM_080812, NM_080813, NM_080814, NM_080815, NM_001320951, NM_001368882, NM_001368884, NM_001368885, NM_001368895, NM_001368896, NM_001368898, NM_001368883, NM_001368886, NM_001368897
• UniProt ID: Q5TAT6
• Synonyms: CMS19; COLXIIIA1
• Summary: This gene encodes the alpha chain of one of the nonfibrillar collagens. The function of this gene product is not known, however, it has been detected at low levels in all connective tissue-producing cells so it may serve a general function in connective tissues. Unlike most of the collagens, which are secreted into the extracellular matrix, collagen XIII contains a transmembrane domain and the protein has been localized to the plasma membrane. The transcripts for this gene undergo complex and extensive splicing involving at least eight exons. Like other collagens, collagen XIII is a trimer; it is not known whether this trimer is composed of one or more than one alpha chain isomer. A number of alternatively spliced transcript variants have been described, but the full length nature of some of them has not been determined. [provided by RefSeq, Jul 2008]