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Human CCR3 activation kit by CRISPRa

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SKU
GA100868
CCR3 CRISPRa kit - CRISPR gene activation of human C-C motif chemokine receptor 3
  $1,657.00
4 Weeks*

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Other products for "CCR3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CCR3
Locus ID 1232
Components

GA100868G1, CCR3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100868G2, CCR3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100868G3, CCR3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001164680, NM_001837, NM_178328, NM_178329
UniProt ID P51677
Synonyms CC-CKR-3; CD193; CKR3; CMKBR3
Summary The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. provided by RefSeq, Sep 2009
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Other Versions
SKU Description Size Price
KN410337 CCR3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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