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Human CCR1 activation kit by CRISPRa

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SKU
GA100867
CCR1 CRISPRa kit - CRISPR gene activation of human C-C motif chemokine receptor 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ug
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Other products for "CCR1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CCR1
Locus ID 1230
Components

GA100867G1, CCR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100867G2, CCR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100867G3, CCR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001295
UniProt ID P32246
Synonyms CD191; CKR-1; CKR1; CMKBR1; HM145; MIP1aR; SCYAR1
Summary This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
KN408605 CCR1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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