Human TPP1 activation kit by CRISPRa

SKU
GA100857
TPP1 CRISPRa kit - CRISPR gene activation of human tripeptidyl peptidase 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TPP1
Locus ID 1200
Components

GA100857G1, TPP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100857G2, TPP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100857G3, TPP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_000391
UniProt ID O14773
Synonyms CLN2; GIG1; LPIC; SCAR7; TPP-1
Summary This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
KN404471 TPP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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