Human CLIC1 activation kit by CRISPRa

SKU GA100852

CLIC1 CRISPRa kit - CRISPR gene activation of human chloride intracellular channel 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: CLIC1
• Locus ID: 1192
• Components:

  GA100852G1, CLIC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100852G2, CLIC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100852G3, CLIC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001287593, NM_001287594, NM_001288
• UniProt ID: O00299
• Synonyms: G6; NCC27
• Summary: Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity. [provided by RefSeq, Jul 2008]