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Human CISH activation kit by CRISPRa

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SKU
GA100828
CISH CRISPRa kit - CRISPR gene activation of human cytokine inducible SH2 containing protein
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC206496 CISH (Myc-DDK-tagged)-Human cytokine inducible SH2-containing protein (CISH), transcript variant 2
10 ug
$300.00

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CISH
Locus ID 1154
Components

GA100828G1, CISH gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100828G2, CISH gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100828G3, CISH gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_013324, NM_145071
UniProt ID Q9NSE2
Synonyms BACTS2; CIS; CIS-1; G18; SOCS
Summary The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Aug 2008
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Other Versions
SKU Description Size Price
KN406496 CISH - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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