Human CIDE A (CIDEA) activation kit by CRISPRa

SKU
GA100825
CIDEA CRISPRa kit - CRISPR gene activation of human cell death inducing DFFA like effector a
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CIDEA
Locus ID 1149
Components

GA100825G1, CIDE A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100825G2, CIDE A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100825G3, CIDE A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001279, NM_001318383, NM_198289, NR_036468, NR_134607
UniProt ID O60543
Synonyms CIDE-A
Summary This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified. provided by RefSeq, Aug 2010
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Documents
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Other Versions
SKU Description Size Price
KN405790 CIDEA - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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