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Human CHRNB4 activation kit by CRISPRa

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SKU
GA100820
CHRNB4 CRISPRa kit - CRISPR gene activation of human cholinergic receptor nicotinic beta 4 subunit
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC218853 CHRNB4 (Myc-DDK-tagged)-Human cholinergic receptor, nicotinic, beta 4 (CHRNB4)
10 ug
$289.00 $457.00

Other products for "CHRNB4"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CHRNB4
Locus ID 1143
Components

GA100820G1, CHRNB4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100820G2, CHRNB4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100820G3, CHRNB4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000750, NM_001256567
UniProt ID P30926
Synonyms cholinergic receptor, nicotinic, beta 4; cholinergic receptor, nicotinic, beta polypeptide 4; neuronal nicotinic receptor beta 4 subunit
Summary This gene is found within a conserved gene cluster and encodes one of the beta subunits of the nicotinic acetylcholine receptor (nAChRs) superfamily which form ligand-gated ion channels with a central pore that forms a cation channel. Neuronal nAChRs are pentameric structures that can be either homomeric or heteromeric, with heteromeric structures containing both alpha and beta subunits. Each subunit contains an extracellular amino terminus and four transmembrane domains. Nicotine is one of the agonists that binds to the receptor. Variants in this gene have been associated with nicotine dependence and lung cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Sep 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN418853 CHRNB4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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