Human CHRNA5 activation kit by CRISPRa

SKU GA100815

CHRNA5 CRISPRa kit - CRISPR gene activation of human cholinergic receptor nicotinic alpha 5 subunit

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: CHRNA5
• Locus ID: 1138
• Components:

  GA100815G1, CHRNA5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100815G2, CHRNA5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100815G3, CHRNA5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_000745, NM_001307945
• UniProt ID: P30532
• Synonyms: LNCR2
• Summary: The protein encoded by this gene is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2).[provided by RefSeq, Jun 2010]