Human Chimaerin 2 (CHN2) activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | CHN2 |
| Locus ID | 1124 |
| Components |
GA100804G1, Chimaerin 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100804G2, Chimaerin 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100804G3, Chimaerin 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001039936, NM_001293069, NM_001293070, NM_001293071, NM_001293072, NM_001293073, NM_001293075, NM_001293076, NM_001293077, NM_001293078, NM_001293079, NM_001293080, NM_001293081, NM_004067, NR_120524, NR_120525 |
| UniProt ID | P52757 |
| Synonyms | ARHGAP3; BCH; CHN2-3; RHOGAP3 |
| Summary | This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that contains a phorbol-ester/diacylglycerol (DAG)-type zinc finger, a Rho-GAP domain, and an SH2 domain. The encoded protein translocates from the cytosol to the Golgi apparatus membrane upon binding by diacylglycerol (DAG). Activity of this protein is important in cell proliferation and migration, and expression changes in this gene have been detected in cancers. A mutation in this gene has also been associated with schizophrenia in men. Alternative transcript splicing and the use of alternative promoters results in multiple transcript variants. provided by RefSeq, May 2014 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| KN411342 | CHN2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
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Citations
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