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Human RCC1 activation kit by CRISPRa

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SKU
GA100786
RCC1 CRISPRa kit - CRISPR gene activation of human regulator of chromosome condensation 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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Other products for "RCC1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol RCC1
Locus ID 1104
Components

GA100786G1, RCC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100786G2, RCC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100786G3, RCC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001048194, NM_001048195, NM_001048199, NM_001269, NR_030725, NR_030726
UniProt ID P18754
Synonyms CHC1; RCC1-I; SNHG3-RCC1
Summary Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis (PubMed:1944575, PubMed:17435751, PubMed:20668449, PubMed:22215983, PubMed:11336674). Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis (PubMed:12194828, PubMed:17435751, PubMed:22215983). Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import (PubMed:22215983). Involved in the regulation of onset of chromosome condensation in the S phase (PubMed:3678831). Binds both to the nucleosomes and double-stranded DNA (PubMed:17435751, PubMed:18762580).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN403556 RCC1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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