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Human DPP1 (CTSC) activation kit by CRISPRa

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SKU
GA100775
CTSC CRISPRa kit - CRISPR gene activation of human cathepsin C
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC214863 CTSC (Myc-DDK-tagged)-Human cathepsin C (CTSC), transcript variant 1
10 ug
$686.00

Other products for "CTSC"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CTSC
Locus ID 1075
Components

GA100775G1, DPP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100775G2, DPP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100775G3, DPP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001114173, NM_001814, NM_148170
UniProt ID P53634
Synonyms CPPI; DPP-I; DPP1; DPPI; HMS; JP; JPD; PALS; PDON1; PLS
Summary This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. provided by RefSeq, Nov 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN214863 CTSC - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214863BN CTSC - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214863LP CTSC - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214863RB CTSC - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN414863 CTSC - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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