Human CENPE activation kit by CRISPRa

SKU
GA100766
CENPE CRISPRa kit - CRISPR gene activation of human centromere protein E
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CENPE
Locus ID 1062
Components

GA100766G1, CENPE gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100766G2, CENPE gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100766G3, CENPE gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001286734, NM_001813
UniProt ID Q02224
Synonyms CENP-E; KIF10; MCPH13; PPP1R61
Summary Centrosome-associated protein E (CENPE) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. This protein is required for stable spindle microtubule capture at kinetochores which is a necessary step in chromosome alignment during prometaphase. This protein also couples chromosome position to microtubule depolymerizing activity. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. provided by RefSeq, Nov 2014
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Other Versions
SKU Description Size Price
KN424375 CENPE - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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