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Human p18 INK4c (CDKN2C) activation kit by CRISPRa

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SKU
GA100743
CDKN2C CRISPRa kit - CRISPR gene activation of human cyclin dependent kinase inhibitor 2C
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA801185 CDKN2C (p18 INK4c) mouse monoclonal antibody, clone OTI6D3 (formerly 6D3) 100 ul
$447.00
RC213083 CDKN2C (Myc-DDK-tagged)-Human cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) (CDKN2C), transcript variant 1
10 ug
$300.00

Other products for "CDKN2C"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CDKN2C
Locus ID 1031
Components

GA100743G1, p18 INK4c gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100743G2, p18 INK4c gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100743G3, p18 INK4c gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001262, NM_078626
UniProt ID P42773
Synonyms INK4C; p18; p18-INK4C
Summary The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN413083 CDKN2C - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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