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Human CDC42 activation kit by CRISPRa

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SKU
GA100712
CDC42 CRISPRa kit - CRISPR gene activation of human cell division cycle 42
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC214076 CDC42 (Myc-DDK-tagged)-Human cell division cycle 42 (GTP binding protein, 25kDa) (CDC42), transcript variant 1
10 ug
$300.00

Other products for "CDC42"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CDC42
Locus ID 998
Components

GA100712G1, CDC42 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100712G2, CDC42 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100712G3, CDC42 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001039802, NM_001791, NM_044472
UniProt ID P60953
Synonyms CDC42Hs; G25K
Summary The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. provided by RefSeq, Apr 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN414076 CDC42 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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