Human CDC25C activation kit by CRISPRa

SKU GA100709

CDC25C CRISPRa kit - CRISPR gene activation of human cell division cycle 25C

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: CDC25C
• Locus ID: 995
• Components:

  GA100709G1, CDC25C gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100709G2, CDC25C gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100709G3, CDC25C gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001287582, NM_001287583, NM_001318098, NM_001790, NM_022809, NM_001364028, NM_001364026, NM_001364027
• UniProt ID: P30307
• Synonyms: CDC25; PPP1R60
• Summary: This gene encodes a conserved protein that plays a key role in the regulation of cell division. The encoded protein directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It also suppresses p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Dec 2015]