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Human CD153 (TNFSF8) activation kit by CRISPRa

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SKU
GA100666
TNFSF8 CRISPRa kit - CRISPR gene activation of human TNF superfamily member 8
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA358538 TNFSF8 Antibody - N-terminal region
100 ul
$585.00
RC211276 TNFSF8 (Myc-DDK-tagged)-Human tumor necrosis factor (ligand) superfamily, member 8 (TNFSF8)
10 ug
$300.00

Other products for "TNFSF8"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TNFSF8
Locus ID 944
Components

GA100666G1, CD153 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100666G2, CD153 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100666G3, CD153 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001244, NM_001252290
UniProt ID P32971
Synonyms CD30L; CD30LG; CD153
Summary The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Nov 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN411276 TNFSF8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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