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Human CD27 activation kit by CRISPRa

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SKU
GA100661
CD27 CRISPRa kit - CRISPR gene activation of human CD27 molecule
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CD27
Locus ID 939
Components

GA100661G1, CD27 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100661G2, CD27 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100661G3, CD27 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001242
UniProt ID P26842
Synonyms S152; S152. LPFS2; T14; TNFRSF7; Tp55
Summary The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. provided by RefSeq, Jul 2008
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Documents
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Other Versions
SKU Description Size Price
KN404252 CD27 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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