Human Cyclin C (CCNC) activation kit by CRISPRa

SKU GA100626

CCNC CRISPRa kit - CRISPR gene activation of human cyclin C

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: CCNC
• Locus ID: 892
• Components:

  GA100626G1, Cyclin C gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100626G2, Cyclin C gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100626G3, Cyclin C gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001013399, NM_005190, NM_001363537
• UniProt ID: P24863
• Synonyms: CycC
• Summary: The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]