Human RUNX3 activation kit by CRISPRa

SKU
GA100608
RUNX3 CRISPRa kit - CRISPR gene activation of human RUNX family transcription factor 3
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol RUNX3
Locus ID 864
Components

GA100608G1, RUNX3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100608G2, RUNX3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100608G3, RUNX3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001031680, NM_001320672, NM_004350
UniProt ID Q13761
Synonyms AML2; CBFA3; PEBP2aC
Summary This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. provided by RefSeq, Mar 2016
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Other Versions
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KN203597 RUNX3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN203597RB RUNX3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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