Human CACNA1S activation kit by CRISPRa

SKU GA100544

CACNA1S CRISPRa kit - CRISPR gene activation of human calcium voltage-gated channel subunit alpha1 S

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: CACNA1S
• Locus ID: 779
• Components:

  GA100544G1, CACNA1S gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100544G2, CACNA1S gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100544G3, CACNA1S gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_000069
• UniProt ID: Q13698
• Synonyms: CACNL1A3; Cav1.1; CCHL1A3; HOKPP; HOKPP1; hypoPP; MHS5; TTPP1
• Summary: This gene encodes one of the five subunits of the slowly inactivating L-type voltage-dependent calcium channel in skeletal muscle cells. Mutations in this gene have been associated with hypokalemic periodic paralysis, thyrotoxic periodic paralysis and malignant hyperthermia susceptibility. [provided by RefSeq, Jul 2008]