Human PTTG1IP activation kit by CRISPRa

SKU GA100523

PTTG1IP CRISPRa kit - CRISPR gene activation of human PTTG1 interacting protein

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PTTG1IP
• Locus ID: 754
• Components:

  GA100523G1, PTTG1IP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100523G2, PTTG1IP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100523G3, PTTG1IP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001286822, NM_004339, NR_104597
• UniProt ID: P53801
• Synonyms: C21orf1; C21orf3; PBF
• Summary: This gene encodes a single-pass type I integral membrane protein, which binds to pituitary tumor-transforming 1 protein (PTTG1), and facilitates translocation of PTTG1 into the nucleus. Coexpression of this protein and PTTG1 induces transcriptional activation of basic fibroblast growth factor. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2013]