Human BUB1 activation kit by CRISPRa

SKU
GA100486
BUB1 CRISPRa kit - CRISPR gene activation of human BUB1 mitotic checkpoint serine/threonine kinase
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol BUB1
Locus ID 699
Components

GA100486G1, BUB1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100486G2, BUB1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100486G3, BUB1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001278616, NM_001278617, NM_004336
UniProt ID O43683
Synonyms BUB1A; BUB1L; hBUB1
Summary This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants. provided by RefSeq, Jul 2013
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Other Versions
SKU Description Size Price
KN407013 BUB1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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