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Human Osteocalcin (BGLAP) activation kit by CRISPRa

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SKU
GA100429
BGLAP CRISPRa kit - CRISPR gene activation of human bone gamma-carboxyglutamate protein
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA321966 Anti-BGLAP Rabbit Polyclonal Antibody
100 ul
$305.00
RC220555 BGLAP (Myc-DDK-tagged)-Human bone gamma-carboxyglutamate (gla) protein (BGLAP)
10 ug
$150.00

Other products for "BGLAP"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol BGLAP
Locus ID 632
Components

GA100429G1, Osteocalcin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100429G2, Osteocalcin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100429G3, Osteocalcin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000711, NM_199173
UniProt ID P02818
Synonyms BGP; bone gamma-carboxyglutamate (gla) protein; bone gamma-carboxyglutamate (gla) protein (osteocalcin); bone Gla protein; gamma-carboxyglutamic acid-containing protein; OC; Osteocalcin; OTTHUMP00000016586; PMF1
Summary This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. provided by RefSeq, Jun 2015
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Documents
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Other Versions
SKU Description Size Price
KN420555 BGLAP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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