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Human bcl 6 (BCL6) activation kit by CRISPRa

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SKU
GA100415
BCL6 CRISPRa kit - CRISPR gene activation of human BCL6 transcription repressor
  $1,657.00
4 Weeks*

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Other products for "BCL6"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol BCL6
Locus ID 604
Components

GA100415G1, bcl 6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100415G2, bcl 6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100415G3, bcl 6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001130845, NM_001134738, NM_001706, NM_138931
UniProt ID P41182
Synonyms BCL5; BCL6A; LAZ3; ZBTB27; ZNF51
Summary The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. provided by RefSeq, Aug 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN419007 BCL6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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