Human BCKDHB activation kit by CRISPRa

SKU
GA100408
BCKDHB CRISPRa kit - CRISPR gene activation of human branched chain keto acid dehydrogenase E1 subunit beta
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol BCKDHB
Locus ID 594
Components

GA100408G1, BCKDHB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100408G2, BCKDHB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100408G3, BCKDHB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000056, NM_001318975, NM_183050, NR_134945
UniProt ID P21953
Synonyms BCKDE1B; BCKDH E1-beta; E1B
Summary This gene encodes the E1 beta subunit of branched-chain keto acid dehydrogenase, which is a multienzyme complex associated with the inner membrane of mitochondria. This enzyme complex functions in the catabolism of branched-chain amino acids. Mutations in this gene have been associated with maple syrup urine disease (MSUD), type 1B, a disease characterized by a maple syrup odor to the urine in addition to mental and physical retardation and feeding problems. Alternative splicing at this locus results in multiple transcript variants. provided by RefSeq, Jan 2016
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Other Versions
SKU Description Size Price
KN408059 BCKDHB - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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